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All parts of the brain › Compare two parts › Hippocampus vs amygdala

Hippocampus vs amygdala: where is each, and what is the difference?

Both sit deep in the inner (medial) part of each temporal lobe and both count as parts of the limbic system, but they do different jobs: the hippocampus turns short-term memories into long-term ones and supports spatial memory, while the amygdala has a primary role in processing memory, decision-making and emotional responses such as fear, anxiety and aggression. [1][2][3]

Measured from the model: the centre of the left amygdala is 20 mm from the centre of the left hippocampus in a straight line [4].

The 3D brain needs JavaScript. The legend and the table below still say where each part is.

Slice

The hippocampus is lit in blue, the amygdala in orange. Drag to turn, pinch or scroll to zoom; tap a part on the brain or in the legend to name it on its own; .

Side by side

Compared Hippocampus Amygdala
Where it isIn the medial temporal lobe of each hemisphere: a curved fold of three-layered cortex (archicortex) that bulges into the floor of the lower (inferior) horn of the lateral ventricle. [1]Medially within each temporal lobe: a nuclear complex, a cluster of grey-matter nuclei inside the hemisphere rather than a fold of cortex. [2]
What it doesConsolidates information from short-term memory into long-term memory, and supports spatial memory, the memory that lets you navigate. [1]Processes memory, decision-making and emotional responses; it plays a role in expressing fear and in processing fear-inducing stimuli. [2]
Connects withMain input from the entorhinal cortex; main output through the fornix, whose fibres run on through the hypothalamus to the mammillary bodies. [5][6]Its basolateral complex links with prefrontal, temporal and insular cortex and with the hippocampus; its central nucleus projects to the brainstem; its cortical and medial nuclei connect with the smell system and the hypothalamus. [2]
Size measured from the model43 mm front to back, 22 mm top to bottom, 20 mm side to side [4]18 mm front to back, 13 mm top to bottom, 17 mm side to side [4]

Size is the box each part fits in on this one model (left hippocampus; left amygdala), not its volume. Real brains vary. A part that comes as a left and a right copy is measured on its left copy; the right one mirrors it.

How far apart are they?

Measured from the model [4], from the left hippocampus to the left amygdala:

  • Centre to centre: 20 mm in a straight line.
  • The centre of the left amygdala is 20 mm further forward, level top to bottom and 1 mm closer to the midline than the centre of the left hippocampus.
  • Nearest points of the two shapes: under 1 mm apart.

A “centre” here is the average position of the points on the part’s 3D surface, so for a curved part such as a C shape it can sit outside the part itself. The nearest-points figure is measured between the corners of the simplified meshes, so a gap of 2 or 3 mm or less is within the model’s coarseness: read it as “touching or nearly so”.

How to tell them apart

  • The hippocampus is named after its shape: in 1587 the anatomist Julius Caesar Aranzi likened the ridge on the floor of the ventricle to a seahorse, hippocampus in Latin. [1]
  • They are wired to each other: the amygdala’s basolateral complex connects extensively with the hippocampus. [2]

Sources

  1. Wikipedia: Hippocampus
  2. Wikipedia: Amygdala
  3. Wikipedia: Limbic system
  4. BodyParts3D 4.0 (3D model measured on this page), © DBCLS, CC BY-SA 2.1 Japan
  5. Wikipedia: Entorhinal cortex
  6. Wikipedia: Fornix (neuroanatomy)

Facts describe anatomy and normal function only. The 3D model is the adult male BodyParts3D brain (credits and licence); real brains vary in size and shape, so its measurements describe one model, not anyone’s brain. Compare other pairs.