brainlocation

For learning, not medical advice.

All parts of the brain › Compare two parts › Thalamus vs hypothalamus

Thalamus vs hypothalamus: where is each, and what is the difference?

The hypothalamus lies below the thalamus (hypo- is Greek for “under”), and together they make up the diencephalon, between the cerebrum and the midbrain. The thalamus relays sensory and motor signals to the cerebral cortex; the hypothalamus links the nervous system to the hormone (endocrine) system through the pituitary gland. [1][2][3]

Measured from the model: the centre of the hypothalamus is 28 mm from the centre of the left thalamus in a straight line [4].

The 3D brain needs JavaScript. The legend and the table below still say where each part is.

Slice

The thalamus is lit in blue, the hypothalamus in orange. Drag to turn, pinch or scroll to zoom; tap a part on the brain or in the legend to name it on its own; .

Side by side

Compared Thalamus Hypothalamus
Where it isThe upper (dorsal) part of the diencephalon. Paired: the inner surface of each thalamus forms the upper part of a side wall of the third ventricle. [2][5]Below the thalamus, the bottom (basal) part of the diencephalon. On the midline: it lines the lower front side walls of the third ventricle, below the groove that separates it from the thalamus. [1][5]
What it doesRelays sensory and motor signals to the cerebral cortex; every sense except smell passes through it on the way to the cortex. [2][6]Links the nervous system to the endocrine system through the pituitary gland: it makes releasing hormones for the anterior pituitary, and oxytocin and vasopressin that are released from the posterior pituitary. [1]
Connects withFibres fan out to the whole cerebral cortex and every cortical region studied sends fibres back; it also receives the output of the basal nuclei and of the cerebellum. [2][6][7]The pituitary gland, through the infundibulum; the hippocampus, through the fornix to its mammillary bodies; the amygdala, through the stria terminalis. [5][8][9]
Size measured from the model37 mm front to back, 24 mm top to bottom, 24 mm side to side [4]18 mm front to back, 20 mm top to bottom, 17 mm side to side [4]

Size is the box each part fits in on this one model (left thalamus; hypothalamus), not its volume. Real brains vary. A part that comes as a left and a right copy is measured on its left copy; the right one mirrors it.

How far apart are they?

Measured from the model [4], from the left thalamus to the hypothalamus:

  • Centre to centre: 28 mm in a straight line.
  • The centre of the hypothalamus is 22 mm further forward, 12 mm lower and 13 mm closer to the midline than the centre of the left thalamus.
  • Nearest points of the two shapes: about 3 mm apart.

A “centre” here is the average position of the points on the part’s 3D surface, so for a curved part such as a C shape it can sit outside the part itself. The nearest-points figure is measured between the corners of the simplified meshes, so a gap of 2 or 3 mm or less is within the model’s coarseness: read it as “touching or nearly so”.

How to tell them apart

  • In humans the hypothalamus is about the size of an almond. [1]
  • The thalamus is paired, one on each side of the third ventricle, usually joined across it by a flat band, the interthalamic adhesion; the hypothalamus sits on the midline below them. [2][5]

Sources

  1. Wikipedia: Hypothalamus
  2. Wikipedia: Thalamus
  3. Wikipedia: Diencephalon
  4. BodyParts3D 4.0 (3D model measured on this page), © DBCLS, CC BY-SA 2.1 Japan
  5. Wikipedia: Third ventricle
  6. OpenStax Anatomy & Physiology 2e, 13.2 The Central Nervous System
  7. Wikipedia: Cerebellum
  8. Wikipedia: Fornix (neuroanatomy)
  9. Wikipedia: Stria terminalis

Facts describe anatomy and normal function only. The 3D model is the adult male BodyParts3D brain (credits and licence); real brains vary in size and shape, so its measurements describe one model, not anyone’s brain. Compare other pairs.