Where it is
- They lie on the underside of the lateral ventricles near the midline, and open into the third ventricle where its roof meets its front surface. [1]
- In front of each foramen is the fornix, and behind it is the thalamus. [1]
- The columns of the fornix arch down in front of them and behind the anterior commissure. [3]
- The lamina terminalis, the thin front wall of the third ventricle, starts at them and runs down to the base of the optic stalk. [4]
What it does
- They let the cerebrospinal fluid made in the lateral ventricles reach the third ventricle and then the rest of the ventricular system. [1]
- Most cerebrospinal fluid is made in the two lateral ventricles; from there it passes through the interventricular foramina into the third ventricle, then through the cerebral aqueduct to the fourth ventricle. [5]
- Their walls contain choroid plexus, the tissue that makes the fluid, continuous with the plexus of the lateral ventricles above and the third ventricle below. [1]
Connections
- End branches of the medial posterior choroidal arteries, and the superior thalamostriate, superior choroid and septal veins, also pass through them. [1]
- In development the lateral ventricles grow as outpouchings of the third ventricle and stay joined to it throughout; the foramina take shape slowly, moving forward and outward as the fornix grows. [1]
Inside it
- Not tissue but openings: each is a hole (Latin foramen, plural foramina) through which cerebrospinal fluid flows. [1]
Other names
- Also called the foramina of Monro, after the Scottish physician Alexander Monro, who described one in 1764 and again in his 1783 Observations on the Structure and Functions of the Nervous System. The eponym is disputed: authors back to Galen had noted that the ventricles connect. [1]
Size
- Each is normally crescent-shaped, and becomes rounder and larger with the size of the lateral ventricles. [1]
- Monro described one as “an oval hole, large enough to admit a goose quill”. [1]
- On this model the one shape the atlas draws for both interventricular foramina measures about 5 mm front to back, 11 mm top to bottom and 13 mm side to side (the box it fits in, not its volume). [2]
- Centre of the interventricular foramina compared with the centre of the left fornix: 14 mm further forward, 9 mm higher, 12 mm closer to the midline; 20 mm apart in a straight line. [2]
- Centre of the interventricular foramina compared with the centre of the left thalamus: 18 mm further forward, 8 mm higher, 12 mm closer to the midline; 23 mm apart in a straight line. [2]